Cisapride Stimulates Contraction of Idiopathic Megacolonic Smooth Muscle in Cats
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چکیده
منابع مشابه
Dynamics of smooth muscle contraction
Photolysis of caged calcium (Nitr5, Calbiochem®) can be used to studycalcium dependent processes such as excitation-contraction coupling andmuscular mechanics. Expensive high energy light sources are routinely used forUV light exposure; this study describes an alternative low cost Xenon flash unitconstmcted in our laboratOlY. A 300 J short arc Xenon flash lamp (Heimarl1l®)wa...
متن کاملATP stimulates Ca2+ oscillations and contraction in airway smooth muscle cells of mouse lung slices.
In airway smooth muscle cells (SMCs) from mouse lung slices, > or =10 microM ATP induced Ca2+ oscillations that were accompanied by airway contraction. After approximately 1 min, the Ca2+ oscillations subsided and the airway relaxed. By contrast, > or =0.5 microM adenosine 5'-O-(3-thiotriphosphate) (nonhydrolyzable) induced Ca2+ oscillations in the SMCs and an associated airway contraction that...
متن کاملATP stimulates Ca oscillations and contraction in airway smooth muscle cells of mouse lung slices
Bergner, Albrecht, and Michael J. Sanderson. ATP stimulates Ca2 oscillations and contraction in airway smooth muscle cells of mouse lung slices. Am J Physiol Lung Cell Mol Physiol 283: L1271–L1279, 2002. First published August 2, 2002; 10.1152/ajplung.00139.2002.—In airway smooth muscle cells (SMCs) from mouse lung slices, 10 M ATP induced Ca2 oscillations that were accompanied by airway contra...
متن کاملExcitation-contraction coupling in airway smooth muscle.
Excitation-contraction (EC) coupling in striated muscles is mediated by the cardiac or skeletal muscle isoform of voltage-dependent L-type Ca(2+) channel (Ca(v)1.2 and Ca(v)1.1, respectively) that senses a depolarization of the cell membrane, and in response, activates its corresponding isoform of intracellular Ca(2+) release channel/ryanodine receptor (RyR) to release stored Ca(2+), thereby in...
متن کاملVascular smooth muscle contraction in hypertension
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia, and chronic kidney disease. Pathophysiological mechanisms contributing to the development of hypertension include increased vascular resistance, determined in large part by reduced vascular diameter due to increased vascular contraction and arterial remo...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 1997
ISSN: 0891-6640,1939-1676
DOI: 10.1111/j.1939-1676.1997.tb00472.x